The Mysterious Way CBD Oil Can Heal Your Skin Problems

The Mysterious Way CBD Oil Can Heal Your Skin Problems

Note: Been using CBD topically and can say it totally works, not only for skin but anxiety. We use the best Endoca
The Mysterious Way CBD Oil Can Heal Your Skin Problems


“Once upon a time, people thought of their skin as a passive “wall” that should be polished so that it will glow. Instead, think of it as a complex organ that contains neuronal networks, it is constantly self-remodeling itself, and modifying non-neuronal cells and mini-organs like the hair follicle and sebaceous glands. It is also a place where immunological machinery is involved in inflammation and immune defense. and a factory of growth factors, vasoactive chemicals, and hormones.

The skin is a “feeling machine”, and it has to be because it is the means by which we interact with our environment.”

The skin is one of the many organs that is equipped with the endocannabinoid system. You may have heard about anandamine. Discovered by Rapahel Mechoulam in 1992, this is one great detective story. If humans have receptors for cannabinoids, CB1, and CB2, there has to be a natural chemical that binds to those receptors. Mechoulam and his coworkers found and characterized that natural chemical, anandamide. 2-arachidonoylglycerol is another natural ligand.

It happens that the skin also has receptors for anandamide. There is not much we can do to increase our endogenous anandamide levels, although chocolate contains chemicals resembling anandamide and I have no doubt that chocolate helps. The good news is that cannabidiol (CBD) is now allowed in skincare products and CBD could help with some skin problems. Let me tell you why.

The cannabinoid signaling extends to the skin and is involved in the maintenance of skin homeostasis, barrier formation, and regeneration. Disruption of the cutaneous cannabinoid system may be involved in several skin diseases and disorders, like atopic dermatitis, psoriasis, scleroderma, acne, hair loss, pigmentation disorders, keratin diseases, and itch. (Sivak, H. Will your skin care for cannabidiol (CBD)?.)

The Mysterious Way CBD Oil Can Heal Your Skin Problems

the skin is a complex system that receives signals from the rest of the body and sends signals that allow us to respond to changes in the environment. Illustration by Magda Levy.

Cannabidiol is perhaps the most interesting compound; furthermore, it lacks the psychoactive properties of THC and is not subjected to heavy legislation. In addition, in contrast with the action of THC, it does not increase the level of β-endorphins in the plasma and in the hypothalamus.

CBD and Skin

There are plausible mechanisms for cannabidiol to have positive effects on skin.

“The cosmetic and skin care interest in CBD is justified by the fact that keratinocytes contain both types of cannabinoid receptors. This does indeed suggest that the skin might be affected when particular molecules bind to these receptors in the keratinocytes, perhaps by modulating wheal and flare in inflammatory reactions or by reducing the pain and discomfort associated with a range of skin conditions. Studies with cultured cells and animal models support this hypothesis.”

The skin has its own endocannabinoid system consisting of cannabinoid receptors which CBD can modulate. Most skin disorders result from some kind of imbalance that is manifested through inflammation. CBD can help restore that state of equilibrium through the signaling of the ECS.

The topical administration of CBD ointment, without any THC, is a safe and effective non-invasive alternative for improve the quality of life in patients with some skin disorders, especially on inflammatory background.

Can CBD Be Absorbed Through the Skin?

Dr. Awais Spall, a chemist and cannabis researcher specializing in skincare, claims that CBD is the next novel treatment for a wide range of skin conditions.

“We’ve recently discovered that the outer layer of our skin, the epidermis, has a dense network of CB1 and CB2 receptors. CBD interacts with these pathways and other nerve channels across the epidermis and dermis.”

When you use a CBD topical, the CBD interacts with the outer layer of the skin, penetrating it to reach the CB2 receptors and modulate the activity of the endocannabinoid system. This, in turn, results in antioxidant, anti-inflammatory, neuroprotective, and painkilling effects.


CBD is a more powerful antioxidant than Vitamin C, E, or A . This antioxidant property of CBD (and other cannabinoids) fights free radical damage and stimulates recovery from oxidative stress. Without antioxidants as a part of your skin care routine, oxidative stress can break down collagen, hinder skin’s natural repair process, and trigger inflammation.


Applied topically, CBD binds to a special set of receptors in the skin known as TRPV-1 receptors, where CBD can reduce feelings of pain, heat, and itch.


Inflammation impedes the skin’s natural regenerative process. By reducing inflammation and free radical damage CBD allows the skin to repair itself and correct visible signs of aging.

When your skin problem derives from inflammation or imbalances within the body, you may want to opt for products such as CBD oil, capsules, or edibles.

CBD oil has relatively high bioavailability and ensures fast effects — they usually appear within 15–30 minutes after ingestion.

The Mysterious Way CBD Oil Can Heal Your Skin Problems

The Mysterious Way CBD Oil Can Heal Your Skin Problems

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